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Cohort studies in transgender care
Since 1972 the Amsterdam Cohort of Gender Dysphoria (ACOG) has followed people who present at the gender clinic of the (then) VUmc, now Amsterdam UMC.
Amsterdam Cohort
Since 1972 the Amsterdam Cohort of Gender Dysphoria (ACOG) has followed people who present at the gender clinic of the (then) VUmc, now Amsterdam UMC. It is one of the longest-running cohort studies in the world; outcomes have been published by Wiepjes and colleagues, among others.
ENIGI
The European Network for the Investigation of Gender Incongruence (ENIGI) is a collaboration of European gender clinics (including Amsterdam, Ghent, Hamburg and Oslo) that has been collecting prospective data on hormone treatment and outcomes since 2010.
Swedish population studies
Sweden combines population registries with clinical data, enabling unique epidemiological studies (such as Dhejne 2011 and Bränström 2019). Such registry studies provide large n, but often lack detail on clinical context.
Sources
Wiepjes, C.M., Nota, N.M., de Blok, C.J.M., et al. (2018). The Amsterdam Cohort of Gender Dysphoria Study (1972–2015). Journal of Sexual Medicine, 15(4), 582–590. doi:10.1016/j.jsxm.2018.01.016
Dhejne, C., Lichtenstein, P., Boman, M., et al. (2011). Long-Term Follow-Up of Transsexual Persons Undergoing Sex Reassignment Surgery. PLOS ONE, 6(2), e16885. doi:10.1371/journal.pone.0016885
Bränström, R., Pachankis, J.E. (2019, corrected 2020). Reduction in Mental Health Treatment Utilization Among Transgender Individuals After Gender-Affirming Surgeries. American Journal of Psychiatry, 177(8), 727–734. doi:10.1176/appi.ajp.2019.19010080