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Systematic reviews in gender care
For the Cass Review the University of York carried out several systematic reviews of puberty blockers, cross-sex hormones, social transition and treatment outcomes in young people with gender dysphoria.
York reviews for Cass
For the Cass Review the University of York carried out several systematic reviews of puberty blockers, cross-sex hormones, social transition and treatment outcomes in young people with gender dysphoria. The reviews were published in 2024 in BMJ Archives of Disease in Childhood.
NICE reviews (2020)
In 2020 the British NICE published two evidence reviews which concluded that the evidence for the effects of puberty blockers and cross-sex hormones on psychological wellbeing in young people was of very low quality.
SBU (Sweden) and COHERE (Finland)
The Swedish and Finnish health technology assessment bodies reached similar conclusions. These reviews provide the scientific underpinning for the Scandinavian policy changes.
Sources
Cass, H. (2024). Independent Review of Gender Identity Services for Children and Young People: Final Report. cass.independent-review.uk
Karolinska Universitetssjukhuset (2021). Beslut om hormonbehandling av minderåriga med könsdysfori. SEGM summary
PALKO/COHERE Finland (2020). Recommendation of the Council for Choices in Health Care in Finland: Medical treatments for dysphoria associated with variations in gender identity in minors. English translation (SEGM)