puberteitsremmers.nl
puberty blockers.nl describes itself as a medical and pediatric resource on GnRH agonists for gender dysphoria, built around three questions: what are they, what do they do, and what don’t we know. The site is published by Stichting Genderinfo i.o. and belongs to the same network as genderinfo.nl.
The site emphasizes the limited scientific evidence supporting the treatment and asks why the Netherlands continues to follow an approach that other countries have reconsidered.
What you will find
The resource begins with an explanation of the medication and how it works. It then covers use outside the approved indication, the effects on bone health, brain development, and fertility and sexuality. Separate pages discuss the Dutch Protocol, the reassessment in the United Kingdom, Sweden, Finland, and Denmark, and the current situation in the Netherlands. Articles and a list of sources complete the resource.
Figures and sources on the homepage
The homepage opens with three key figures: zero randomized studies, zero registrations of the medication for this use, and approximately 98 percent of young people who continue with sex hormones after taking puberty blockers. The site names triptorelin as an example of a GnRH agonist. The sources cited are the 2024 final report of the Cass Review, the 2020 NICE review, and a 2021 study by Carmichael and colleagues in PLOS ONE on the short-term outcomes of puberty suppression. The international section covers Sweden’s National Board of Health and Welfare (Socialstyrelsen, 2022), Finland’s COHERE (2020), and Denmark’s Sundhedsstyrelsen (2023). The menu follows the structure of the resource: what the medications are, how they work, use outside the approved indication, harm, the Dutch Protocol, international developments, the current situation in the Netherlands, articles, and sources.
How to read the site
The site states that its content is not medical advice and refers visitors with personal questions to their doctor. The resource is written from a critical perspective and selects its sources accordingly. Anyone seeking a complete picture should also read the authorities that reach different conclusions. For example, on June 30, 2026, the Health Council of the Netherlands concluded that hormone treatments in young people achieve their physical aims and that the available data provide no reason not to offer them. The general explanation on this site can be found in the article about puberty blockers. A related site within the same network is dutchprotocol.nl.
Why it is included in this archive
Puberty blockers are the first step in the Dutch Protocol and are central to the debate about gender-affirming care for young people. This resource explores that single subject in greater depth than a general information site can.